Clobester lotions are topical medications, typically containing corticosteroids like clobetasol, which reduce inflammation, itching, and redness associated with skin conditions such as eczema and psoriasis. Some formulations, like Clobester S6, also contain salicylic acid to help with dry, scaly skin, while others, such as Clobester-F, include an antibiotic like fusidic acid to treat bacterial infections. Clobester lotions are for external use only and should be applied as a thin layer to the affected area as directed by a healthcare professional.